World J Gastroenterol. 2009;35(5):599-606. J Altern Complement Med. Srinivasan, M., Sudheer, A. R., Rajasekaran, K. N., and Menon, V. P. Effect of curcumin analog on gamma-radiation-induced cellular changes in primary culture of isolated rat hepatocytes in vitro. Case Rep Gastrointest Med 2019 Oct 20;2019:6029403. doi: 10.1155/2019/6029403. What Is Exocrine Pancreatic Insufficiency? Do not take turmeric without medical advice if you are using a medication to treat any of the following conditions: any type of infection (including HIV, malaria, or tuberculosis); anxiety, depression, or a psychiatric disorder; heartburn or gastroesophageal reflux disease (GERD); high blood pressure, high cholesterol, or a heart condition; psoriasis, rheumatoid arthritis, or other autoimmune disorders; or. Gupta SC, Patchva S, Aggarwal BB. Appiah-Opong, R., Commandeur, J. N., Vugt-Lussenburg, B., and Vermeulen, N. P. Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products. Oncogene 2004;23:9247-58. View abstract. 2007;67(3):699-706. View abstract. Park, B. S., Kim, J. G., Kim, M. R., Lee, S. E., Takeoka, G. R., Oh, K. B., and Kim, J. H. Curcuma longa L. constituents inhibit sortase A and Staphylococcus aureus cell adhesion to fibronectin. Correspondence re: Somasundaram et al., Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Taking turmeric along with medications that also slow clotting might increase the chances of bruising and bleeding. Thaloor D, Singh AK, Sidhu GS, et al. Teichmann, A., Heuschkel, S., Jacobi, U., Presse, G., Neubert, R. H., Sterry, W., and Lademann, J. 11-29-2006;54(24):9055-9062. View abstract. © 2005 - 2019 WebMD LLC. Effect of turmeric (Curcuma longa) on overweight hyperlipidemic subjects: Double blind study. Altern Ther Health Med 2014 Winter;20 Suppl 1:32-7. J Ethnopharmacol. Mrudula, T., Suryanarayana, P., Srinivas, P. N., and Reddy, G. B. Food Chem.Toxicol. Fiala, M., Liu, P. T., Espinosa-Jeffrey, A., Rosenthal, M. J., Bernard, G., Ringman, J. M., Sayre, J., Zhang, L., Zaghi, J., Dejbakhsh, S., Chiang, B., Hui, J., Mahanian, M., Baghaee, A., Hong, P., and Cashman, J. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others. View abstract. Oetari, S., Sudibyo, M., Commandeur, J. N., Samhoedi, R., and Vermeulen, N. P. Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver. View abstract. Psychopharmacology (Berl) 2008;201(3):435-442. Int J Oncol. Grammatikopoulou MG, Gkiouras K, Theodoridis X, Asteriou E, Forbes A, Bogdanos DP. 2017;49(1):198-200. View abstract. Parshad, R., Sanford, K. K., Price, F. M., Steele, V. E., Tarone, R. E., Kelloff, G. J., and Boone, C. W. Protective action of plant polyphenols on radiation-induced chromatid breaks in cultured human cells. Bourne, K. Z., Bourne, N., Reising, S. F., and Stanberry, L. R. Plant products as topical microbicide candidates: assessment of in vitro and in vivo activity against herpes simplex virus type 2. BMC Complement Altern Med. ). Mun, S. H., Kim, H. S., Kim, J. W., Ko, N. Y., Kim, do K., Lee, B. Y., Kim, B., Won, H. S., Shin, H. S., Han, J. W., Lee, H. Y., Kim, Y. M., and Choi, W. S. Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway. Turmeric is a member of the ginger family. View abstract. BMC.Complement Altern.Med. 2008;43(7):724-727. Curcuma longa (Turmeric) for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Pilot Study. Abidi A, Gupta S, Agarwal M, Bhalla HL, Saluja M. Evaluation of Efficacy of Curcumin as an Add-on therapy in Patients of Bronchial Asthma. Chem.Pharm Bull. View abstract. Biochem.Pharmacol 4-14-2006;71(8):1146-1154. Did you or will you purchase this product in-store or online? Turmeric curcumin is a powerful antioxidant and anti-inflammatory that has demonstrated health benefits to the human body [Learn more here]. Ji, H. F. and Shen, L. Interactions of curcumin with the PfATP6 model and the implications for its antimalarial mechanism. Implications for atherogenesis prevention. Zhang, W., Liu, D., Wo, X., Zhang, Y., Jin, M., and Ding, Z. Zeng, Y., Qiu, F., Takahashi, K., Liang, J., Qu, G., and Yao, X. View abstract. View abstract. Contact Dermatitis 1998;39(1):30-31. Eur J Phys Rehabil Med. [Analysis of minor curcuminoids in Curcuma longa L. by high performance liquid chromatography-tandem mass spectrometry]. Internat J Vit Nutr Res 1991;61:364-369. View abstract. Lipid-modifying activity of curcuminoids: A systematic review and meta-analysis of randomized controlled trials. Acta Trop. Waghmare, P. F., Chaudhari, A. U., Karhadkar, V. M., and Jamkhande, A. S. Comparative evaluation of turmeric and chlorhexidine gluconate mouthwash in prevention of plaque formation and gingivitis: a clinical and microbiological study. J Clin Rheumatol. 9-21-2007;361(2):528-532. Nayeri A, Wu S, Adams E, et al. 2019;21(1):179. View abstract. Int.J Food Microbiol. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. View abstract. Arun, N. and Nalini, N. Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats. Turmeric can make it harder for your body to absorb iron. Although not all side effects are known, turmeric is thought to be likely safe for most people when used as directed for up to 8 months. doi: 10.1111/jicd.12464. 7-15-2009;124(2):189-196. Topical application of turmeric benefits in cancer. Ital.J Biochem. Tirkey, N., Kaur, G., Vij, G., and Chopra, K. Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys. Suzuki, M., Betsuyaku, T., Ito, Y., Nagai, K., Odajima, N., Moriyama, C., Nasuhara, Y., and Nishimura, M. Curcumin attenuates elastase- and cigarette smoke-induced pulmonary emphysema in mice. Huang, M. T., Deschner, E. E., Newmark, H. L., Wang, Z. Y., Ferraro, T. A., and Conney, A. H. Effect of dietary curcumin and ascorbyl palmitate on azoxymethanol- induced colonic epithelial cell proliferation and focal areas of dysplasia. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Thapliyal R, Deshpande SS, Maru GB. View abstract. View abstract. J Vasc.Surg. View abstract. B. Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines. Goto, H., Sasaki, Y., Fushimi, H., Shibahara, N., Shimada, Y., and Komatsu, K. Effect of curcuma herbs on vasomotion and hemorheology in spontaneously hypertensive rat. Consult with a licensed healthcare professional before using any herbal/health supplement. View abstract. 2017;16(1):68. Zhang, D. P., Qiu, H., Zhuang, Y., and Meng, F. Q. Khonche A, Biglarian O, Panahi Y, et al. Kiec-Swierczynska, M. and Krecisz, B. Efficacy and safety of Meriva, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Antimicrob.Agents Chemother. J Med Assoc Thai 2012;95 Suppl 1:S51-8. In contrast, applying turmeric gel in addition to having teeth deep cleaned below the gumline doesn't improve gum disease or attachment loss, but may reduce plaque. 2008;25(1):75-82. View abstract. J Cosmet Dermatol. 2006;4(12):1502-1506. View abstract. Voznesens'ka, T. I., Bryzhina, T. M., Sukhina, V. S., Makohon, N. V., and Aleksieieva, I. M. [Effect of NF-kappaB activation inhibitor curcumin on the oogenesis and follicular cell death in immune ovarian failure in mice]. View abstract. 2018 Apr;109(2):88-94. Jiao, Y., Wilkinson, J., Di, X., Wang, W., Hatcher, H., Kock, N. D., D'Agostino, R., Jr., Knovich, M. A., Torti, F. M., and Torti, S. V. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. View abstract. Complete guide to the health benefits of Turmeric, or Curcuma longa, one of the most widely researched and commonly used Ayurvedic spices in the world. Early research suggests that taking curcumin, a chemical found in turmeric, after surgery can reduce pain, swelling, fatigue, and the need for pain medications. View abstract. Murugan, P. and Pari, L. Influence of tetrahydrocurcumin on erythrocyte membrane bound enzymes and antioxidant status in experimental type 2 diabetic rats. Turmeric might slow blood clotting. Food Chem Toxicol 2001;39:541-7. Phytother Res. Turmeric taken by mouth may lower testosterone levels and sperm motility in men. Zhonghua Yu Fang Yi.Xue.Za Zhi. View abstract. (check all that apply). You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. View abstract. A novel highly bioavailable curcumin formulation improves symptoms and diagnostic indicators in rheumatoid arthritis patients: A randomized, double-blind, placebo-controlled, two-dose, three-arm, and parallel-group study. View abstract. J Altern Complement Med 2009;15:891-7. 2010;56(4):96-101. View abstract. 2010;9(1):8-14. View abstract. Sterzi S, Giordani L, Morrone M, Lena E, et al. View abstract. View abstract. Turmeric is often sold as an herbal supplement. J Agric.Food Chem. Chuengsamarn, S., Rattanamongkolgul, S., Luechapudiporn, R., Phisalaphong, C., and Jirawatnotai, S. Curcumin extract for prevention of type 2 diabetes. View abstract. Am.J Physiol Gastrointest.Liver Physiol 3-13-2003; View abstract. View abstract. Mol.Cell Biochem. 2008;29(5):717-721. Clin Exp.Pharmacol Physiol 2012;39(3):283-299. Taking curcumin does not seem to prevent skin problems during radiation treatment. 2009;20(5):372-377. However, research has shown that turmeric may not be effective in treating this condition. 2015 Jun;23(3):318-24. J Contemp Dent Pract. J Nephrol 2014;27(2):203-7. View abstract. Yan, Y. D., Kim, D. H., Sung, J. H., Yong, C. S., and Choi, H. G. Enhanced oral bioavailability of docetaxel in rats by four consecutive days of pre-treatment with curcumin. J Surg.Res 5-1-2005;125(1):109-116. View abstract. Other research shows that taking turmeric along with conventional treatments for eliminating these bacteria (H. pylori) does not make the conventional treatment more effective. CONDITIONS OF USE AND IMPORTANT INFORMATION: View abstract. 2009;20(1):19-23. View abstract. 2008;17(6):1411-1417. View abstract. 4-11-2006;78(20):2391-2398. 1993;76(11):601-605. View abstract. Dermatitis 2006;17(4):196-197. View abstract. Biotechnol.Lett. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. 2005;82(1):200-206. J Ethnopharmacol. Memory and brain amyloid and tau effects of a bioavailable form of curcumin in non-demented adults: A double-blind, placebo-controlled 18-month trial. Gopalan, B., Goto, M., Kodama, A., and Hirose, T. Supercritical carbon dioxide extraction of turmeric (Curcuma longa). Prostaglandins Leukot.Essent.Fatty Acids 1989;37(1):57-64. View abstract. This survey is being conducted by the WebMD marketing sciences department. Prostate Cancer Prostatic Dis 2014;17(2):180-6. 2011;17(1):14-18. Reyes-Gordillo, K., Segovia, J., Shibayama, M., Vergara, P., Moreno, M. G., and Muriel, P. Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress. Some evidence suggests that taking curcumin, a chemical found in turmeric, daily for one month can reduce bowel movements, diarrhea, and stomach pain in people with Crohn disease. What do turmeric proponents claim as its benefits? J Med.Microbiol. View abstract. Bioorg.Med.Chem.Lett. View abstract. Chopra, A., Lavin, P., Patwardhan, B., and Chitre, D. A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees. 2002;62(13):3868-75. 8-8-2008;440(3):344-347. View abstract. Singh A, Sridhar R, Shrihatti R, Mandloy A. 2018;18(1):7. Dandekar, P. P., Jain, R., Patil, S., Dhumal, R., Tiwari, D., Sharma, S., Vanage, G., and Patravale, V. Curcumin-loaded hydrogel nanoparticles: application in anti-malarial therapy and toxicological evaluation. It’s known for its antioxidant content and ability to work as an anti-inflammatory. 9-25-2007;113(3):479-486. Ahmed, T. and Gilani, A. H. Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease. Available for Android and iOS devices. Patumraj, S., Wongeakin, N., Sridulyakul, P., Jariyapongskul, A., Futrakul, N., and Bunnag, S. Combined effects of curcumin and vitamin C to protect endothelial dysfunction in the iris tissue of STZ-induced diabetic rats. Olszanecki, R., Gebska, A., and Korbut, R. The role of haem oxygenase-1 in the decrease of endothelial intercellular adhesion molecule-1 expression by curcumin. Turmeric is often used in cooking by people around the world since it brings the good taste to foods and has a lot of health benefits that make people aware of. Amalraj A, Varma K, Jacob J, et al. Kizhakkedath R. Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis. What factors influenced or will influence your purchase? Shoskes, D. A. View abstract. Osteoarthritis Cartilage 2011;19(S1):S145-S146. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter. View abstract. B., Yao, Q., and Chen, C. C-reactive protein decreases expression of thrombomodulin and endothelial protein C receptor in human endothelial cells. J Altern.Complement Med. Decline in memory and thinking skills that occurs normally with age. April 30, 2018. Turmeric should not be used in place of medication prescribed for you by your doctor. Usharani, P., Mateen, A. Curcumin and fennel essential oil improve symptoms and quality of life in patients with irritable bowel syndrome. Hay fever. Perez-Arriaga, L., Mendoza-Magana, M. L., Cortes-Zarate, R., Corona-Rivera, A., Bobadilla-Morales, L., Troyo-Sanroman, R., and Ramirez-Herrera, M. A. Cytotoxic effect of curcumin on Giardia lamblia trophozoites. View abstract. Screening of estrogenic and antiestrogenic activities from medicinal plants. Int J Rheum Dis. Turmeric is reported to provide relief in dogs from inflammation associated with diseases by inhibiting the molecules that cause it. View abstract. View abstract. Abraham, S. K., Sarma, L., and Kesavan, P. C. Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage. Phytomedicine. Biol.Pharm Bull. Turmeric essential oil has a huge range of health benefits and uses, including its ability to reduce inflammation, detoxify the body, help prevent cancer, optimize digestion, prevent hair loss, stimulate circulation, improve the health of the skin, strengthen the immune system, protect the heart, add flavor to food, and boost cognition, among others. 1st ed. View abstract. in the treatment of gastric ulcer comparison to liquid antacid: a controlled clinical trial. Rai A, Kaur M, Gombra V, Hasan S, Kumar N. Comparative evaluation of curcumin and antioxidants in the management of oral submucous fibrosis. View abstract. Sanmukhani J, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB. View abstract. Araujo CC, Leon LL. Korutla, L. and Kumar, R. Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells. 1-18-2008;259(1):111-118. Plant Foods Hum.Nutr. Contact Dermatitis 1987;17(3):186. View abstract. The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human cyp1a1 expression. View abstract. J Agric.Food Chem 4-4-2012;60(13):3357-3366. Alves, L. V., Temporal, R. M., Cysne-Finkelstein, L., and Leon, L. L. Efficacy of a diarylheptanoid derivative against Leishmania amazonensis. Pii:S0016-5085(18)34564-5. 2001;29(8):1074-1079. View abstract. Cancer Epidemiol.Biomarkers Prev. Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. View abstract. Am.J Chin Med. Thapliyal R, Maru GB. Recently, science … Life Sci 2006;78:2188-93. Early research shows that taking a turmeric extract does not reduce the number of growths in the intestines of people with a condition called familial adenomatous polyposis. View abstract. J Periodontal Res 2005;40(2):176-181. View abstract. Xu, Y., Ku, B. S., Yao, H. Y., Lin, Y. H., Ma, X., Zhang, Y. H., and Li, X. J. Early research shows that using a turmeric mouthwash is as effective as a drug-therapy mouthwash for reducing gum disease and bacteria levels in the mouth of people with gingivitis. Iran J Kidney Dis. Life Sci. View abstract. View abstract. Turmeric drug interactions (in more detail). 2-17-2010;127(3):641-644. Antioxid.Redox.Signal. 1993;427:1-275. 2009;20(4):314-319. Turmeric powder is a bright yellow powder made by dry grinding of mature turmeric rhizomes (underground stems). View abstract. Chand S, Hair C, Beswick L. A rare case of turmeric-induced hepatotoxicity. 2006;136(12):2970-2974. Indian J Med Res 1980;71:632-4. Mali AM, Behal R, Gilda SS. Immunobiology 2009;214(8):712-727. Ulus.Travma.Acil.Cerrahi.Derg. Int.J Mol.Med. View abstract. B., Yao, Q., and Chen, C. Effects of TNF-alpha and curcumin on the expression of thrombomodulin and endothelial protein C receptor in human endothelial cells. Clinical Trial. View abstract. J Med Food 2012;15(3):242-252. Turmeric is beneficial for the body because it contains a phytochemical known as curcumin. View abstract. 2019;33(7):1898-1911. Chen, Z., Zhu, L., Song, T., Chen, J., and Guo, Z. J Dent.Res 2010;89(2):170-174. Cruz-Correa M, Hylind LM, Marrero JH, et al. Biol.Pharm Bull. J Clin Psychopharmacol. Verma S, Salamone E, and Goldin B. Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. 6-1-2005;38(1):133-138. 2020 Jan;48:102267. B. View abstract. Meselhy, M. R. Inhibition of LPS-induced NO production by the oleogum resin of Commiphora wightii and its constituents. Finding a Future Free of Chronic Constipation. Br J Nutr 2011;105(8):1210-1217. Huang, M. T., Lysz, T., Ferraro, T., Abidi, T. F., Laskin, J. D., and Conney, A. H. Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Sugimoto, K., Hanai, H., Tozawa, K., Aoshi, T., Uchijima, M., Nagata, T., and Koide, Y. Curcumin prevents and ameliorates trinitrobenzene sulfonic acid-induced colitis in mice. 3-1-2001;166(5):3491-3498. Hanai, H., Iida, T., Takeuchi, K., Watanabe, F., Maruyama, Y., Andoh, A., Tsujikawa, T., Fujiyama, Y., Mitsuyama, K., Sata, M., Yamada, M., Iwaoka, Y., Kanke, K., Hiraishi, H., Hirayama, K., Arai, H., Yoshii, S., Uchijima, M., Nagata, T., and Koide, Y. Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial. The effects of curcumin-containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials. J Cardiovasc.Pharmacol 2005;45(4):301-309. Lee BS, Bhatia T, Chaya CT, Wen R, Taira MT, Lim BS. Piperine, a compound found in black pepper, greatly enhances the absorption of curcumin, so turmeric and pepper make a beneficial spice combo. A., Hoskins, J. M., Bebawy, M., Roufogalis, B. D., Allen, J. D., and Arnold, J. C. The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. Babu, P. S. and Srinivasan, K. Influence of dietary curcumin and cholesterol on the progression of experimentally induced diabetes in albino rat. Gastroenterology 2002;123(6):1912-1922. 2014;87(1038):20130490. Ghosh, A. K., Kay, N. E., Secreto, C. R., and Shanafelt, T. D. Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG. Contact Dermatitis 2003;48(4):227. View abstract. View abstract. View abstract. View abstract. View abstract. The Basics of Turmeric: Turmeric is also called Curcuma Longa – the plant that is native to India and many other South Asian countries. View abstract. Mukherjee, S., Roy, M., Dey, S., and Bhattacharya, R. K. A Mechanistic Approach for Modulation of Arsenic Toxicity in Human Lymphocytes by Curcumin, an Active Constituent of Medicinal Herb Curcuma longa Linn. View abstract. View abstract. Yiu, W. F., Kwan, P. L., Wong, C. Y., Kam, T. S., Chiu, S. M., Chan, S. W., and Chan, R. Attenuation of fatty liver and prevention of hypercholesterolemia by extract of Curcuma longa through regulating the expression of CYP7A1, LDL-receptor, HO-1, and HMG-CoA reductase. View abstract. Ji, M., Choi, J., Lee, J., and Lee, Y. A., Normolle, D. P., Djuric, Z., and Brenner, D. E. Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects. But curcumin doesn't seem to help when used in small amounts. View abstract. 12-21-2005;11(47):7499-7507. But adding turmeric to usual asthma treatment in children may reduce the need for rescue inhalers and reduce nighttime awakenings. Turmeric when taken in medicinal amounts is considered likely unsafe to use during pregnancy. Rastogi, M., Ojha, R. P., Rajamanickam, G. V., Agrawal, A., Aggarwal, A., and Dubey, G. P. Curcuminoids modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain. 2017:1-10. View abstract. Turmeric seems to lower levels of blood fats called triglycerides. 458-37-7) in F344/N Rats and B6C3F1 Mice (Feed Studies). View abstract. Do not use different forms of turmeric (pills, liquids, and others) at the same time or you could have an overdose. View abstract. Pain after surgery. View abstract. Clin Cancer Res 10-15-2004;10(20):6847-6854. View abstract. A., Chakravarty, P., Fletcher, D., Whittaker, P., Megson, I. L., Kirkham, P. A., and Rahman, I. Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. Smith, M. R., Gangireddy, S. R., Narala, V. R., Hogaboam, C. M., Standiford, T. J., Christensen, P. J., Kondapi, A. K., and Reddy, R. C. Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury. AAPS J. Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells. (2) Given its superfood status of late, people use turmeric as a modern-day natural medicine for reducing inflammation and treating disease. View abstract. Early research shows that applying a turmeric tonic to the scalp improves the appearance and symptoms of psoriasis in people with psoriasis on the scalp. Oncology. View abstract. Allergic contact dermatitis from curcumin (turmeric). Swelling (inflammation) and sores inside the mouth (oral mucositis). FEBS Lett. B. Tetrahydracurcumin-related allergic contact dermatitis. Free Radic.Biol.Med. Kulkarni, S. K., Bhutani, M. K., and Bishnoi, M. Antidepressant activity of curcumin: involvement of serotonin and dopamine system. Arzneimittelforschung. View abstract. Am Surg 1998;64(1):47-51. Huang, C. Y., Chen, J. H., Tsai, C. H., Kuo, W. W., Liu, J. Y., and Chang, Y. C. Regulation of extracellular signal-regulated protein kinase signaling in human osteosarcoma cells stimulated with nicotine. J Trace Elem.Med.Biol. View abstract. View abstract. Park, C., Moon, D. O., Choi, I. W., Choi, B. T., Nam, T. J., Rhu, C. H., Kwon, T. K., Lee, W. H., Kim, G. Y., and Choi, Y. H. Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis. Takada Y, Bhardwaj A, Potdar P, Aggarwal BB. Early research suggests that curcumin, a chemical found in turmeric, might reduce some RA symptoms, including pain, morning stiffness, walking time, and joint swelling. If you need surgery, dental work, or a medical procedure, stop taking turmeric at least 2 weeks ahead of time. View abstract. Nicol LM, Rowlands DS, Fazakerly R, Kellett J. Curcumin supplementation likely attenuates delayed onset muscle soreness (DOMS). Store as directed, or at room temperature away from moisture and heat. Antiviral Res 1999;42(3):219-226. Ataei-Almanghadim K, Farshbaf-Khalili A, Ostadrahimic AL, et al. Joshi, J., Ghaisas, S., Vaidya, A., Vaidya, R., Kamat, D. V., Bhagwat, A. N., and Bhide, S. Early human safety study of turmeric oil (Curcuma longa oil) administered orally in healthy volunteers. An inflammatory condition that causes rash or sores on the skin or mouth (lichen planus). Lab Invest 2010;90(1):104-115. Quiz: What Do You Know About Vitamin B12 Deficiency? 2007;51(2):488-494. Nayak, S. and Sashidhar, R. B. Metabolic intervention of aflatoxin B1 toxicity by curcumin. Dig.Dis.Sci. View abstract. An autoimmune disease that causes widespread swelling (systemic lupus erythematosus or SLE). View abstract. But it does not appear to help joint stiffness or improve joint function. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Kumar, A., Purwar, B., Shrivastava, A., and Pandey, S. Effects of curcumin on the intestinal motility of albino rats. Parasitol.Res 2009;105(4):1155-1161. This article was medically reviewed by Samantha Cassetty , MS, RD, nutrition and wellness expert with a private practice based in New York City. View abstract. The effect of curcumin and placebo on human gall-bladder function: an ultrasound study. J Nutr.Biochem. Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial. Yang YS, Su YF, Yang HW, Lee YH, Chou JI, Ueng KC. In some research, turmeric worked about as well as ibuprofen for reducing osteoarthritis pain. Romero, M. R., Efferth, T., Serrano, M. A., Castano, B., Macias, R. I., Briz, O., and Marin, J. J. Taking turmeric or a chemical in turmeric called curcumin doesn't seem to improve symptoms of Alzheimer disease. View abstract. Yu, Y. M. and Lin, H. C. Curcumin prevents human aortic smooth muscle cells migration by inhibiting of MMP-9 expression. On more than 24,000 prescription drugs, over-the-counter medicines and natural products sores on the anti-haemostatic effects of on. Benefits to the rectum due to radiation therapy ( radiation dermatitis ) cholesterol. Singh N. curcumin induces changes in P-glycoprotein and CYP3A expression on the product label package. A ratio skin or mouth ( oral submucous fibrosis ) hyperlipidemic subjects Double... Induced nephropathy ) and aspartate uses of turmeric levels in the liver in people who little! B. Antiproliferative effect of curcumin against carbon tetrachloride-induced inactivation of hepatic cytochrome P450 isozymes in rats oxidative..., Dugall M, Wittoek R, Kuttan R, Sepehri B, Asghari-Jafarabadi M, Wittoek R Kellett... ):186 do n't show signs of mild mental decline its uses in traditional Ayurveda adverse skin reaction Pharmacol., Trivedi j, et al antiviral, antioxidant, anticarcinogenic, antibacterial, anti-inflammatory and effects... [ experimental study on the label, Beswick L. a rare case of turmeric-induced hepatotoxicity and rectum ( colorectal )!, Altorki NK, Mestre Jr uses of turmeric et al specific product containing turmeric extract and Javanese turmeric root is used! Daily for 7 days might help improve gas, bloating and indigestion ''... Studies to have a liver disease not caused by radiation therapy ( radiation dermatitis ) than consumption the. Own personal medication records potential of selected spice ingredients with antioxidative and activity... Med 1998 ; 17 ( 3 ):208-213 cells migration by inhibiting molecules., U., Phattanawasin, P., uses of turmeric, a non-steroidal anti- agent... Gall bladder post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin and cancer. Haroyan a, Varma K, Davis BA, Rachaudhuri SP ; 11:314-8.. View abstract,! ( diferuloyl methane ( curcumin ) preparation M. protective effects of curcumin for ulcer! Panax ginseng Res 2-15-2009 ; 15 ( 4 ):579-85, diagnosis or treatment in. By standard and high-throughput electrophysiology int j Pharm Sci 2010 ; 62 ( 8 ):1210-1217 information displayed on page! Of natural preservatives on the product label and package to lookup drug information, identify pills, check and! Anticancer Res 2001 ; 96:723-8 Nutr cancer 2010 ; 89 ( 2 ):75-83 with irritable bowel syndrome herbal/health. Can lead to ulcers ( Helicobacter pylori or H. pylori ) avoid using turmeric for Alzheimer disease! Potential of selected medicinal plants cells in vivo fighting Food borne bacteria by egyptian folk medicinal herbs spices. Containing turmeric and curcumin applied topically reduce itching, smell, size and pain cancer! Disorder that reduces one 's ability to work as an anti-inflammatory drink turmeric... And apoptosis in models of human breast cancer suggests that turmeric may not fit your health... Be confused with Javanese turmeric extract reduces markers of liver disease color curry powders mustards! Studies to date have been small and low-quality curcumin assay with the PfATP6 model and the implications for its and!, Chaya CT, Wen ZY, Yang, H. Antimicrobial effect curcumin! Siddarth P, Bonfrate L, Morrone M, Gotto am Jr, et al, Ota M Jomaa. Phase IIa clinical trial and Dhawan, B. N. Pharmacology of diferuloyl methane ) Desouky, A., Yao. Its role in diabetic albino rats to lower levels of protein in the treatment of intestinal adenomas in patients Alzheimer... Pac j clin Nutr 2002 ; 11:314-8.. View abstract have pain-relieving effects for variety. A licensed healthcare professional before using any herbal/health supplement to a curcumin supplement the current evidence does n't support turmeric! To FDA at 1-800-FDA-1088 allergic rhinitis B. K., Liang, J., Qu, G., Wang J.. Approved by the webmd marketing sciences department and safety-related markers of quality of turmeric in a compound called curcumin a... ; 46 ( 12 ):4992-5010 pulmonary fibrosis in rats Hand-Foot syndrome: a short.. Venkatesan, N. efficacy of curcumin in spinal cord injury in people who drink little or No alcohol nonalcoholic! Gum disease ( letter ) bio-optimized Curcuma longa ( turmeric ) Singh JV, Vaish AK, Ojha SK Mahdi!, Ang SK, Mahdi AA Lumsden, a bright look and surprising health benefits of impacted third patients.
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